【讲座通知】伦敦帝国理工学院Prof. Paul Langford|胸膜肺炎放线杆菌:从毒理机制到治愈方案
时间:2015年11月26日(星期四)13:30-14:30
地点:新加坡国立大学苏州研究院创新中心(苏州工业园区林泉街377号公共学院3号楼1楼)
主题:Actinobacillus pleuropneumoniae: from understanding virulence towards eradication
Prof. Paul LangfordPhD. Professor Professor of Paediatric Infectious Diseases Imperial College London
Abstract: In regard to antimicrobial resistance we have focussed on the pig pathogen A. pleuropneumoniae and developed high throughput genome wide mutagenesis protocols and screens (based on Transposon Directed Insertion site Sequencing [TraDIS]) to identify genes essential for growth in vitro and in vivo, with a view to developing novel antimicrobial and vaccine strategies. The methods developed are applicable to other pathogenic members of the Pasteurellaceae i.e. Aggregatibacter actinomycetemcomitans, H. influenzae, Mannheimia haemolytica, and P. multocida.