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张勇

张勇

张勇

首席研究员

biezy@nus.edu.sg

教育背景:

浙江大学博士


研究领域:

1. 纳米生物材料和纳米医学
2. 生物医学微型设备


荣誉、奖项:

1. 获德国“洪堡研究奖”

2. 入选全球评高被引科学家

3. 获英国皇家化学学会奖学金
4. 新国大教务长教授职位
5. 新加坡杰出工程成就奖

6. NML研究员奖

7. 新国大青年研究员奖


著作:

1. Jayakumar MK and Zhang Y, Rare Earth Nanomaterials in Fluorescence Microscopy. In Rare Earth Materials in Nanotechnology. ed. Timothy Tan Thatt Yany, 55-78. Singapore: Pan Stanford Publishing Pte. Ltd, 2012.
2. Tan TTY, Liu S, Zhang Y, Han MY and Selvan ST, Microemulsion Preparative Methods (Overview). In Comprehensive Nanoscience and Technology, 399-441. Maryland Heights: Elsevier B.V., 2010. 43 pp.
3. Amalraj AI and Zhang Y, Upconverting Fluorescent Nanoparticles for Biological Applications. In Emerging Nanotechnologies for manufacturing, ed. Waqar Ahmed and M.J. Jackson. Micro and Nano Technologies, vol. 978-0-08-094763-1. New York: Elsevier Science, 2009. 20 pp.
4. Chatterjee DK and Zhang Y, Lanthanide Doped Upconverting Nanoparticles for Biomedical Applications. In Doped Nanomaterials and Nanodevices, ed. Wei Chen. California: American Scientific Publishers, 2008. 20 pp.
5. Zhang Y and Wang F, Use of nanoparticles as building blocks for bioapplications. In Molecular Building Blocks for Nanotechnology: From Diamondoids to Nanoscale Materials and Applications, ed. G. A. Mansoori, T. F. George, L. Assoufid and G. P. Zhang, 353-376. Topics in Applied Physics, vol. 109. BERLIN: SPRINGER-VERLAG BERLIN, 2007. 24 pp.


代表性论文:

[1] Lei, Z.; Ling, X.; Mei, Q.; Fu, S.; Zhang, J.; Zhang, Y. “Anisotropic Energy Migration: An Excitation Navigating Energy Migration of Lanthanide Ions in Upconversion Nanoparticles”. Advanced Materials 2020, 32(9), 2070068.
[2] Teh, D. B. L.; Bansal, A.; Chai, C.; Toh, T. B.; Tucker, R. A. J.; Gammad, G. G. L.; Yeo, Y.; Lei, Z.; Zheng, X.; Yang, F.; Ho, J. S.; Bolem, N; Wu, B. C.; Gnanasammandhan, M. K.; Hooi, L.; Dawe, G. S.; Libedinsky, C.; Ong, W. Y.; Halliwell, B.; Chow, E. K. H.; Lim, K. L.; Zhang, Y.; Kennedy, B. K. “A Flexi‐PEGDA Upconversion Implant for Wireless Brain Photodynamic Therapy”. Advanced Materials 2020, 2001459.
[3] Zhang, Z.; Jayakumar, M. K. G.; Zheng, X.; Shikha, S.; Zhang, Y.; Bansal, A.; Poon, D. J. J.; Chu, P. L.; Yeo, E. L. L.; Chua, M. L. K.et al. “Upconversion superballs for programmable photoactivation of therapeutics”. Nature Communications 2019, 10, Article Number 4586.
[4] Tang, M.; Zhu, X. H.; Zhang, Y. H.; Zhang, Z. P.; Zhang, Z. M.; Mei, Q. S.; Zhang, J.; Wu, M. H.; Liu, J. L.; Zhang, Y. “Near-Infrared Excited Orthogonal Emissive Upconversion Nanoparticles for Imaging-Guided On-Demand Therapy”. ACS Nano 2019, 13, 10405.
[5] Mei, Q. S.; Bansal, A.; Jayakumar, M. K. G.; Zhang, Z. M.; Zhang, J.; Huang, H.; Yu, D. J.; Ramachandra, C. J. A.; Hausenloy, D. J.; Soong, T. W.et al. “Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation”. Nature Communications 2019, 10, Article Number 4416.
[6] Zeming, K. K.; Salafi, T.; Shikha, S.; Zhang, Y. “Fluorescent label-free quantitative detection of nano-sized bioparticles using a pillar array”. Nature Communications 2018, 9, Article Number 1254.
[7] Bansal, A.; Yang, F. Y.; Xi, T.; Zhang, Y.; Ho, J. S. “In vivo wireless photonic photodynamic therapy”. Proceedings of the National Academy of Sciences of the United States of America 2018, 115, 1469.
[8] Shikha, S.; Salafi, T.; Cheng, J. T.; Zhang, Y. “Versatile design and synthesis of nano-barcodes”. Chemical Society Reviews 2017, 46 (22), 7054.
[9] Salafi, T.; Zeming, K. K.; Zhang, Y. “Advancements in microfluidics for nanoparticle separation”. Lab on a Chip 2017, 17, 11.
[10] Zeming, K. K.; Thakor, N. V.; Zhang, Y.; Chen, C. H. “Real-time modulated nanoparticle separation with an ultra-large dynamic range”. Lab on a Chip 2016, 16, 75.
[11] Gnanasammandhan, M. K.; Idris, N. M.; Bansal, A.; Huang, K.; Zhang, Y. “Near-IR photoactivation using mesoporous silica-coated NaYF4:Yb,Er/Tm upconversion nanoparticles”. Nature Protocols 2016, 11 (4), 688.
[12] Bansal, A.; Liu, H. C.; Jayakumar, M. K. G.; Andersson-Engels, S.; Zhang, Y. “Quasi-Continuous Wave Near-Infrared Excitation of Upconversion Nanoparticles for Optogenetic Manipulation of C-elegans”. Small 2016, 12 (13), 1732.
[13] Lucky, S. S.; Soo, K. C.; Zhang, Y. “Nanoparticles in Photodynamic Therapy”. Chemical Reviews 2015, 115 (4), 1990.
[14] Lucky, S. S.; Idris, N. M.; Li, Z. Q.; Huang, K.; Soo, K. C.; Zhang, Y. “Titania Coated Upconversion Nanoparticles for Near-Infrared Light Triggered Photodynamic Therapy”. ACS Nano 2015, 9 (1), 191.
[15] Idris, N. M.; Jayakumar, M. K. G.; Bansal, A.; Zhang, Y. “Upconversion nanoparticles as versatile light nanotransducers for photoactivation applications”. Chemical Society Reviews 2015, 44 (6), 1449.


专利:

1. Upconversion Fluorescent Nano-Structure Material and Uses Thereof, US Patent Application No.: 12/445,904, filed on 17/10/2007, US Grant No.: 8,093,566, issued on 10/01/2012.
2. Method of Patterning and Product(s) Obtained Therefrom, PCT/SG2007/000116, filed on 24/04/2007
3. Novel Method for Microbead Patterning and Application Thereof, US provisional patent, 60/795,811, filed on 25/04/2006
4. A New Microfluidic Device for Multiplexed Bead Based Detection, US provisional patent, 60/800,860, filed on 17/05/2006
5. Monodisperse Infrared-to-Visible Upconversion Nanoparticle Phoshors, US provisional patent, 60/829,768, filed on 17/10/2006
6. Novel 3-D Pyramidal Porous-Membrane and its Applications Thereof, US provisional patent (PCT application is being filed), 61/491,395, filed on 31/05/2011


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