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卢一新

卢一新

卢一新

首席研究员

chmlyx@nus.edu.sg

教育背景 

01/1995 – 01/2000 加拿大麦吉尔大学化学系,博士
09/1987 – 07/1991 复旦大学化学系,学士


工作经历

07/2014 – 至今 新加坡国立大学化学系,教授
07/2010 – 06/2014 新加坡国立大学化学系,副教授
01/2005 – 06/2010 新加坡国立大学化学系,助理教授

研究领域

1. 有机小分子催化的不对称反应
2. 过渡金属催化的高选择性不对称反应
3. 以绿色化学为导向的新反应方法和技术
4. 镇痛剂和抗癌药物的合成


奖项/荣誉
Singapore National Research Foundation (NRF) Investigatorship Award, 2018
顾问委员会委员,Accounts of Chemical Research (2017至今)
编辑委员会委员,Asian Journal of Organic Chemistry (from November 2016至今)
Asian Core Program Lectureship Award to China (2017, 2014, 2011) 
Outstanding Scientist Award, Faculty of Science, NUS (2013)
Dean’s Chair Professorship, NUS (2013)
GSKSNIC Award in Organic Chemistry (2013)
Asian Core Program Lectureship Award to Taiwan (2012)
GSKEDB Green & Sustainable Manufacturing Fund Award (2011)
Outstanding Chemist Award, NUS Chemistry (2011)
Young Chemist Award, NUS Chemistry (2010)
Asian Core Program Lectureship Award to Japan (2009)
Asian Core Program Lectureship Award to Korea (2009)
Young Scientist Award, Faculty of Science, NUS (2009)



代表性论文(>150 文章,>7,200 引用, H-Index 52)          

1.  Chan, W.-L.; Tang, X.; Zhang, F.; Quek, G.; Mei, G.-J.; Lu, Y. “Phosphine-Catalyzed (3+2) Annulation of Isoindigos with Allenes: Enantioselective Formation of Two Vicinal Quaternary Stereogenic Centers”, Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201900758.
2.  Li, K.; Goncalves. T. P.; Huang, K.-W.; Lu, Y. “Dearomatization of 3-Nitroindoles via a Phosphine-catalyzed Enantioselective [3+2] Annulation Reaction”, Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201900248. 
3. Ni, H.; Chan, W.-L.; Lu, Y. “Phosphine-catalyzed Asymmetric Organic Reactions”,  Chem. Rev. 2018, 118, 9344.
4.  Li, X.; Gao, Q.; Wang, J.; Chen, Y.; Chen, Z.; Xu, H.-S.; Tang, W.; Leng, K.; Ning, G.-H.; Wu, J.; Xu, Q.-H.; Quek, S. Y.; Lu, Y.; Loh, K. P. “Tuneable Near White-Emissive Two-Dimensional Covalent Organic Frameworks", Nat. Commun. 2018, 9, 2335.
5.  Ni, H.; Tang, X.; Zheng, W.; Yao, W.; Ullah, N.; Lu, Y. “Enantioselective Phosphine-Catalyzed Formal [4+4] Annulation of ,-Unsaturated Imines and Allene Ketones: Construction of Eight-membered Rings”,  Angew. Chem. Int. Ed. 2017, 56, 14222
6. Yao, W.; Dou, X.; Wen, S.; Wu, J.; Lu, Y. “Enantioselective Desymmetrization of Cyclohexadienones via an Intramolecular Rauhut–Currier Reaction of Allenoates”, Nat. Commun., 2016, 7, 13024.
7. Wang, T.; Han, X.; Zhong, F.; Yao, W.; Lu, Y. “Amino Acid-derived Bifunctional Phosphines for Enantioselective Transformations”, Acc. Chem. Res. 2016, 49, 1369.
8.  Han, X.; Chan, W.-L.; Yao, W., Wang, Y.; Lu, Y. Phosphine-mediated Highly Enantioselective Spirocyclization with Ketimines as Substrates”, Angew. Chem. Int. Ed. 2016, 55, 6492.
9.  Wang, T.; Yu, Z.; Hoon, D. L.; Phee, C. Y.; Lan, Y.; Lu, Y. “Regiodivergent Enantioselective -Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of ,-Disubstituted -Amino Acids and N,O-Acetal Derivatives”, J. Am. Chem. Soc. 2016, 138, 265.
10. Dou, X.; Lu, Y.; Hayashi, T. “Base Free Conditions for Rhodium-Catalyzed Asymmetric Arylation to Produce Stereochemically Labile α-Aryl Ketones”, Angew. Chem. Int. Ed. 2016, 55, 6739.


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