教育背景
1981-1985 四川大学化学系，学士
1990-1992 日本大阪大学高分子科学系，硕士
1992-1995 日本大阪大学高分子科学系，博士
工作经历
1985-1987, 四川省化工研究所, 助理工程师
1995-1998, 日本理化学研究所, 基础科学特别研究员
1998-2002, 新加坡材料研究院, 研究员、高级研究员
2002-2007, 新加坡国立大学生物医学工程系, 助理教授
2007-2015, 新加坡国立大学生物医学工程系, 副教授
2015-至今, 新加坡国立大学生物医学工程系, 教授
2022-至今, 新加坡国立大学苏州研究院，首席研究员
研究领域
超分子自组装和高分子纳米结构的基础研究
智能生物材料和水凝胶及其在药物与基因递送，纳米医学中的应用
生物基高分子材料及其在水处理，资源回收，可持续发展等领域的应用
荣誉、奖项
2020, Global Alumni Fellow awarded by Osaka University, Japan
2015, Plenary Speaker, The 4th European Cyclodextrin Conference, Lille, France
2010, Plenary Speaker, The 20th Annual Conference of Australasian Society for Biomaterials and Tissue Engineering (ASBTE 2010), Brisbane, Australia
2009, JSPS (Japan Society for the Promotion of Science) International Fellowship
2008, Invited Lecture of Asia Excellence, The 57th SPSJ (Society of Polymer Science of Japan) Annual Meeting, Japan
1995-1998, RIKEN Special Postdoctoral Fellowship
1995, The Award of Osaka University International Exchange Program in Macromolecular Science
1990-1995, Japanese Government (Monbusho) Graduate Scholarship
代表性论文
[1] Tang X, Wen Y, Zhang Z, Zhu J, Song X, and Li J*, Rationally designed multifunctional nanoparticles as GSH-responsive anticancer drug delivery systems based on host-guest polymers derived from dextran and β-cyclodextrin, Carbohydrate Polymers, 2023, 320, 121207.
[2] Zhang Z, Zhu J, Song X, Wen Y, Zhu C, and Li J*, Biomass-based single- and double-network hydrogels derived from cellulose microfiber and chitosan for potential application as plant growing substrate, Carbohydrate Polymers, 2023, 319, 121170.
[3] Zheng D, Xu X, Zhu J, Bai B*, Wang Q, Shi W, and Li J*, Humidity capture and solar-driven water collection behaviors of alginate-g-PNIPAm-based hydrogel, Journal of Environmental Chemical Engineering, 2023, 11(1), 109247.
[4] Zhu C, Zhang Z, Wen Y, Song X, Zhu J, Yao Y, and Li J*, Cationic micelles as nanocarriers for enhancing intra-cartilage drug penetration and retention, Journal of Materials Chemistry B, 2023, 11, 1670-1683.
[5] Zhu J, Tan WK, Song X, Zhang Z, Gao Z, Wen Y, Ong CN, Swarup S, and Li J*, Synthesis and Characterization of Okara-Poly(acrylic acid) Superabsorbent Hydrogels for Enhancing Vegetable Growth through Improving Water Holding and Retention Properties of Soils, ACS Food Science & Technology, 2023, 3, 553-561.
[6] Soh WWM, Zhu J, Song X, Jain D, Yim EKF,* and Li J*, Detachment of bovine corneal endothelial cell sheets by cooling-induced surface hydration of poly[(R)-3-hydroxybutyrate]-based thermoresponsive copolymer coating, Journal of Materials Chemistry B, 2022, 10, 8407-8418.
[7] Zhang M, Zhang Z, Song X, Zhu J, Li J*, and Wen Y*, Synthesis and Characterization of Palmitoyl-block-poly(methacryloyloxyethyl phosphorylcholine) Polymer Micelles for Anticancer Drug Delivery, Biomacromolecules, 2022, 23, 4586-4596.
[8] Soh WWM, Teoh RYP, Zhu J, Xun Y, Wee CY, Ding J, Thian ES, and Li J*, Facile Construction of a Two-in-One Injectable Micelleplex-Loaded Thermogel System for Prolonged Delivery of Plasmid DNA, Biomacromolecules, 2022, 23, 3477-3492.
[9] Wen Y, Mensah NN, Song X, Zhu J, Tan WS, Chen X, Li J*, Hydrogel with supramolecular surface functionalization for cancer cell capture and multicellular spheroid growth and release, Chemical Communications, 2022, 58, 681-684.
[10] Li H, Peng E, Zhao F, Li J*, Xue JM*, Supramolecular Surface Functionalization of Iron Oxide Nanoparticles with α-Cyclodextrin-Based Cationic Star Polymer for Magnetically Enhanced Gene Delivery, Pharmaceutics, 2021, 13(11), 1884.
[11] Zhang Z, Wen Y, Song X, Zhu J, Li J*, Nonviral DNA Delivery System with Supramolecular PEGylation Formed by Host-Guest Pseudo-Block Copolymers, ACS Applied Bio Materials, 2021, 4, 5057-5070.
[12] Wen Y, Bai H, Zhu J, Song X, Tang G, Li J*, A supramolecular platform for controlling and optimizing molecular architectures of siRNA targeted delivery vehicles, Science Advances, 2020, 6, eabc2148.
[13] Zhu J, Tan WK, Song X, Gao Z, Wen Y, Ong CN, Loh CS, Swarup S, Li J*, Converting okara to superabsorbent hydrogels as soil supplements for enhancing the growth of choy sum (brassica sp.) under water-limited conditions, ACS Sustainable Chemistry & Engineering, 2020, 8(25), 9425-9433.
[14] Zhu J, Song X, Tan WK, Wen Y, Gao Z, Ong CN, Loh CS, Swarup S, Li J*, Chemical modification of biomass okara using poly(acrylic acid) through free radical graft polymerization, Journal of Agricultural and Food Chemistry, 2020, 68 (46), 13241-13246.
[15] Song X, Zhang Z, Zhu J, Wen Y, Zhao F, Lei L, Phan-Thien N, Khoo BC, Li J*, Thermoresponsive Hydrogel Induced by Dual Supramolecular Assemblies and Its Controlled Release Property for Enhanced Anticancer Drug Delivery, Biomacromolecules, 2020, 21, 1516-1527.
[16] Ooi YJ, Wen Y, Zhu JL, Song X, Li J*, Surface charge switchable polymer/DNA nanoparticles responsive to tumor extracellular pH for tumor-triggered enhanced gene delivery, Biomacromolecules, 2020, 21 (3), 1136−1148.
[17] Liu M, Wen YT, Song X, Zhu JL, Li J*, A smart thermoresponsive adsorption system for efficient copper ion removal based on alginate-g-poly(N-isopropylacrylamide) graft copolymer, Carbohydrate Polymers, 2019, 219, 280-289.
[18] Zhu JL, Yu SWK, Chow PKH, Tong YW, Li J*, Controlling injectability and in vivo stability of thermogelling copolymers for delivery of yttrium-90 through intra-tumoral injection for potential brachytherapy, Biomaterials, 2018, 180, 163-172.
[19] Wen Y & Li J*, Ultrastable micelles boost chemotherapy, Nature Biomedical Engineering, 2018, 2, 273–274.
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